Life Sciences

Life Scences and Quantum Imaging

Biomedical imaging is an area where QuantIC seeks to expand its contributions.  These will primarily be in the areas of through body imaging and microscopy.

Imaging Through the Body

Recently QuantIC has shown that combining spatial and temporal measurement alongside advanced computational techniques enables reconstruction of the precise shape (1mm resolution) of objects embedded within 5cm of opaque material. Working with industry we will demonstrate imaging of objects embedded in opaque media that have absorption and scattering coefficients similar to those of human tissue. Target parameters are: >10cm of tissue, <1mm resolution at sub-second acquisition times.

Imaging Through Single Fibres

An endoscope comprising just one optical fibre presents the smallest, least invasive, solution.  The challenge in transmitting an image through a single fibre is the cross-talk between modes which causes scrambling of the image. We will combine single photon timing, high-speed beam shaping and neural networks to learn the transmission matrix of a fibre and reconstruct high quality images at video-rate through long (10m) fibres. Our ambition is to create a new generation of single fibre endoscope that can produce full 3D images of remote scenes and  transmit them over long distances.

Microscopy with Quantum Illumination

Conventional microscopes have diffraction-limited resolution. By using position-correlated photon-pairs to illuminate the sample and a software optimised EMCCD camera we can beat this limit and also eliminate stray light. In preliminary work, we have demonstrated feasibility, albeit requiring hours of data collection. We aim to achieve video rate imaging below the diffraction limit with total rejection of stray light.

Sub Shot Noise Imaging

QuantIC has used correlated photon pairs to suppress noise below the classical limit. We will develop new light sources that work at wavelengths and optical powers suitable for real world applications and install them into imaging systems. For example we will use stimulated four wave mixing in optical fibres to create photon pairs at mW powers and use them to produce high quality images with lower optical power (>3db) than required by classical physics.