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QuantIC is collaborating with Glasgow-based Horiba Jobin Yvon IBH Limited in assessing the feasibility of multiplexed time-correlated single photon timing fluorescence systems.
The phenomenon of fluorescence provides a multidimensional signature of a molecule and is widely used for analysis and research, for example in sequencing the human genome and disease diagnostics. The fluorescence signature of a molecule carries information that includes the wavelengths of excitation and emission (colour), the intensity of the emitted light (brightness), the characteristic time for emission (decay time), polarization (alignment), position (image) and yield (efficiency).
However, at present all commercially available fluorescence instrumentation accesses only a small fraction of this information and requires many sequential measurements over a long period of time to build up a complete molecular fluorescence signature.
QuantIC’s researchers at the University of Strathclyde and University of Edinburgh will assess the feasibility of adding multiplexed (imaging) detection systems to Horiba’s range of instruments in order to speed up measurements, which will open up new applications, for example in the study of transient species.
This project is being led by Professor David Birch from the University of Strathclyde.
The HORIBA Group of worldwide companies provides an extensive array of instruments and systems for applications ranging from automotive R&D, process and environmental monitoring, in-vitro medical diagnostics, semiconductor manufacturing and metrology, to a broad range of scientific R&D and QC measurements. HORIBA Jobin Yvon Ltd was established in 1989 and is one of the world’s largest manufacturers of analytical and spectroscopic systems and components.For more information, please visit www.horiba.com/uk/manufacturing/glasgow